{"product_id":"b-12-vitamin-injection-cyanocobalamin-1000mcg-mdv-ml-25-pack","title":"B-12 Vitamin Injection Cyanocobalamin 1000MCG MDV\/ml 25\/Pack","description":"\u003cp\u003e\u003cstrong\u003eNDC:\u003c\/strong\u003e 72603-650-25\u003c\/p\u003e\n\u003ch3\u003eCyanocobalamin Injection, USP 1,000 mcg\/mL, 25 x 1 mL Multiple-Dose Vials — NorthStar Rx\u003c\/h3\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eActive ingredient\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eCyanocobalamin 1,000 mcg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDosage form\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eInjection, solution, multiple-dose vial (contains benzyl alcohol 1.5% as preservative; contains no more than 625 mcg\/L aluminum)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eRoute\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eIntramuscular, Subcutaneous\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSize\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e25 x 1 mL multiple-dose vials\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eManufacturer\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eManufactured by Mankind Pharma Limited; manufactured for NorthStar Rx LLC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eNDC\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e72603-650-25\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch4\u003eIndications and Usage\u003c\/h4\u003e\n\u003cp\u003eIndicated for vitamin B12 deficiencies due to malabsorption, which may be associated with pernicious (Addisonian) anemia, gastrointestinal pathology\/dysfunction\/surgery (including gluten enteropathy, small bowel bacterial overgrowth, total or partial gastrectomy), fish tapeworm infestation, malignancy of the pancreas or bowel, or folic acid deficiency. Also suitable for use in the vitamin B12 absorption test (Schilling test).\u003c\/p\u003e\n\u003ch4\u003eDosage and Administration\u003c\/h4\u003e\n\u003cp\u003eAvoid intravenous administration; the vitamin is nearly completely lost in the urine via this route. For pernicious anemia: 100 mcg intramuscularly or by deep subcutaneous injection daily for 6–7 days, then on alternate days for 7 doses, then every 3–4 days for 2–3 weeks, followed by 100 mcg monthly for life. For the Schilling test, the flushing dose is 1,000 mcg. Inspect visually for particulate matter and discoloration prior to administration.\u003c\/p\u003e\n\u003ch4\u003eWarnings and Precautions\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003eContains benzyl alcohol, which has been associated with fatal \"Gasping Syndrome\" in premature infants\u003c\/li\u003e\n\u003cli\u003eContains aluminum, which may reach toxic levels with prolonged parenteral use in patients with impaired kidney function, including premature neonates\u003c\/li\u003e\n\u003cli\u003eAnaphylactic shock and death have been reported with parenteral vitamin B12 administration; an intradermal test dose is recommended in patients suspected of sensitivity\u003c\/li\u003e\n\u003cli\u003ePatients with early Leber's disease (hereditary optic nerve atrophy) have suffered severe and swift optic atrophy following cyanocobalamin treatment\u003c\/li\u003e\n\u003cli\u003eHypokalemia and sudden death may occur during intensive treatment of severe megaloblastic anemia; serum potassium should be monitored closely during the first 48 hours of treatment\u003c\/li\u003e\n\u003cli\u003eFolic acid should not be substituted for vitamin B12; doing so may mask hematologic improvement while allowing irreversible neurologic damage to progress\u003c\/li\u003e\n\u003cli\u003ePatients with pernicious anemia have approximately 3 times the incidence of gastric carcinoma versus the general population; appropriate testing should be performed when indicated\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eContraindications\u003c\/h4\u003e\n\u003cp\u003eContraindicated in patients with known sensitivity to cobalt and\/or vitamin B12.\u003c\/p\u003e\n\u003ch4\u003eAdverse Reactions\u003c\/h4\u003e\n\u003cp\u003eReported reactions include anaphylactic shock and death (parenteral administration); pulmonary edema and congestive heart failure early in treatment; peripheral vascular thrombosis; polycythemia vera; mild transient diarrhea; itching and transitory exanthema; and generalized feeling of body swelling.\u003c\/p\u003e\n\u003ch4\u003eStorage and Handling\u003c\/h4\u003e\n\u003cp\u003eStore at 20°C to 25°C (68°F to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F). Protect from light.\u003c\/p\u003e\n\u003ch4\u003eHow Supplied\u003c\/h4\u003e\n\u003cp\u003eSupplied as a red solution in 1 mL multiple-dose vials, packaged 25 vials per carton.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eProfessional use only. Clinical information summarized from FDA-approved prescribing information (Structured Product Labeling); refer to the full prescribing information via DailyMed for complete details.\u003c\/em\u003e\u003c\/p\u003e","brand":"Northstar Rx","offers":[{"title":"Default Title","offer_id":53655418896749,"sku":"RX-2026","price":39.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/wholesale.dryeyerescue.com\/products\/b-12-vitamin-injection-cyanocobalamin-1000mcg-mdv-ml-25-pack","provider":"Dryeye Rescue Pro","version":"1.0","type":"link"}