Description
Amoxicillin – Broad-Spectrum Antibiotic for Bacterial Infections
Overview
Amoxicillin is a penicillin-class antibacterial medication commonly prescribed to treat infections caused by susceptible bacteria. It is widely used for conditions such as:
- Soft tissue infections – including hordeolum, preseptal cellulitis, dacryocystitis, and dacryoadenitis.
- Upper and lower respiratory tract infections – affecting the ear, nose, throat, and lungs.
- Genitourinary and skin infections – effective against common bacterial strains.
- Helicobacter pylori infections – when used as part of combination therapy for duodenal ulcers.
Amoxicillin is available in multiple dosage forms and strengths to accommodate both adult and pediatric patients.
Key Features
- Broad-Spectrum Effectiveness – Targets a wide range of Gram-positive and Gram-negative bacteria.
- Multiple Formulations – Available in tablets, capsules, chewable tablets, and oral suspension for flexible dosing.
- Pregnancy Category B – Considered safe for use during pregnancy when necessary.
- Pediatric-Friendly – Dosages available for children 3 months and older.
- Convenient Dosing – Taken every 8 to 12 hours, with or without food.
Recommended Dosage for Soft Tissue Infections (Adults)
- 500 mg to 875 mg twice daily for 5-7 days.
- In cases of increasing bacterial resistance, Amoxicillin + Clavulanate (Augmentin) is recommended.
Contraindications & Warnings
- Do not use in patients with a history of severe hypersensitivity reactions to penicillins or cephalosporins.
- May cause serious allergic reactions, including anaphylaxis.
- Severe cutaneous adverse reactions (SCAR), including Stevens-Johnson Syndrome (SJS), may occur.
- Clostridioides difficile-associated diarrhea (CDAD) may develop as a side effect.
- Drug interactions may occur with oral contraceptives, anticoagulants, allopurinol, and probenecid.
Common Side Effects
- Gastrointestinal discomfort – nausea, vomiting, diarrhea.
- Skin reactions – rash, itching.
- Hypersensitivity reactions – swelling, difficulty breathing (seek medical attention immediately).
Available Dosage Forms & Strengths
- Tablets: 500 mg, 875 mg
- Capsules: 250 mg, 500 mg
- Chewable Tablets: 125 mg, 250 mg
- Oral Suspension: 200 mg/5 mL, 250 mg/5 mL, 400 mg/5 mL
Important Usage Information
- Take at the start of a meal to reduce stomach upset.
- Complete the full course of treatment to prevent antibiotic resistance.
- Store oral suspension in the refrigerator and discard after 14 days.
Trusted and Effective Treatment
Amoxicillin has been a gold-standard antibiotic for decades, helping patients recover from bacterial infections safely and effectively. When used as directed by a healthcare professional, it provides reliable relief and supports bacterial eradication.