Optimel Manuka+ Dry Eye Dropâ„¢ helps restore eye comfort and reduces inflammation by improving eye-lid margin hygiene and reducing bacteria that may potentially colonize the eyelid margin causing inflammation, poor tear quality, and trauma to the eye surface.
Patients with tear deficiency and meibomian gland disease have an overgrowth of ocular flora. This overgrowth is thought to contribute to the tear film instability and ocular surface damage. Both topical and systemic antibiotics can significantly reduce the Colony Forming Units (CFUs) in eyes with chronic lid disease. With the increase of resistance among ocular pathogens (Cernak et al 2011), the efficacy of antibiotic therapeutic regimens is being reduced.
Application of Optimel Manuka+ Dry Eye Drop 3 times daily to the inferior conjunctival fornix can significantly reduce CFUs from baseline at month 1 in the eyelids of patients with dry eye caused by tear deficiency and/or meibomian gland disease.
Reduction of CFUs reduces the potential susceptibility of the dry eye patient to bacterial conjunctivitis and keratitis. The reduction in CFUs may also assist in improving the clinical symptoms of dry eye disease by reducing the production of certain bacterial lipases that are thought to hydrolyse meibomian gland lipids.
Albietz and Lenton also reported that the application of medical-grade Leptospermum sp honey (Manuka) was associated with significant clinical improvements in dry eye and meibomian gland dysfunction. The only adverse effects noted with the use of Optimel Manuka+ Dry Eye Drop in the eye are stinging and redness. No serious adverse effects are noted.