Product Information
About the Product
EyePromise PRN DE3 Dry Eye Omega Benefits is a softgel dietary supplement supplying EPA and DHA omega-3 fatty acids in re-esterified triglyceride (rTG) form, from sustainably sourced Norwegian fish oil, together with vitamin D3, available in 90, 180 and 270 count bottles. Each daily serving of three softgels provides 2,240 mg of EPA and DHA at a 3 to 1 EPA to DHA ratio, plus 25 mcg (1,000 IU) of vitamin D3.
People take this as a daily omega-3 supplement, three softgels swallowed with a meal, and it is the softgel alternative to the same formula sold as a liquid. It supports natural tear production and a healthy tear film. The three bottle sizes are the same product at different reorder intervals.
| Size | Servings | Supply at three softgels daily |
|---|---|---|
| 90 softgels | 30 | 1 month |
| 180 softgels | 60 | 2 months |
| 270 softgels | 90 | 3 months |
Key Ingredients
180ct 2 Month Supply
- EPA and DHA, 2,240 mg combined per three softgel serving Long-chain omega-3 fatty acids, supplied here in re-esterified triglyceride (rTG) form at a 3 to 1 EPA to DHA ratio.
- Re-esterified triglyceride fish oil (anchovy, sardine, herring, mackerel) The highly refined and concentrated marine oil that carries the EPA and DHA.
- Vitamin D3, 25 mcg (1,000 IU) per serving A fat-soluble vitamin, included in the same softgel alongside the oil.
- Natural mixed tocopherols (soy derived) A preservative that protects the oil from oxidising.
270ct 3 Month
- EPA and DHA, 2,240 mg combined per three softgel serving Long-chain omega-3 fatty acids, supplied here in re-esterified triglyceride (rTG) form at a 3 to 1 EPA to DHA ratio.
- Re-esterified triglyceride fish oil (anchovy, sardine, herring, mackerel) The highly refined and concentrated marine oil that carries the EPA and DHA.
- Vitamin D3, 25 mcg (1,000 IU) per serving A fat-soluble vitamin, included in the same softgel alongside the oil.
- Natural mixed tocopherols (soy derived) A preservative that protects the oil from oxidising.
90ct 1 Month
- EPA and DHA, 2,240 mg combined per three softgel serving Long-chain omega-3 fatty acids, supplied here in re-esterified triglyceride (rTG) form.
- Re-esterified triglyceride fish oil (anchovy, sardine, herring, mackerel) The highly refined and concentrated marine oil that carries the EPA and DHA.
- Vitamin D3 A fat-soluble vitamin, included in the same softgel alongside the oil.
- Natural mixed tocopherols (soy derived) A preservative that protects the oil from oxidising.
Other Ingredients
Highly Refined and Concentrated Re-esterified Triglyceride Fish Oil (one or more of anchovy, sardine, herring, and mackerel), Capsule Shell (bovine gelatin, glycerin, purified water), Natural Berry/Orange Flavor, Natural Mixed Tocopherols (soy derived preservative)
Allergen Information
No gluten, dairy, or artificial colors or flavors.
How to Use
Three softgels once daily with a meal, or as directed by your healthcare professional.
This product:
- Restores moisture by supporting natural tear production.
- Protects and retains moisture by supporting a healthy tear film.
Warnings
If you are pregnant, nursing, trying to conceive, taking any medications, or have a medical condition, please consult your healthcare practitioner before using this product. Do not take if the tamper-evident seal is broken or missing. Keep out of reach of children.
Storage
Store in a cool, dry place, away from sunlight.
Supplement Disclaimer
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
RescueRating RR 82 out of 100 Evidence: ModerateHow we rated itHide details
How PRN DE3 earned RR 82
Four equal parts, each scored out of 100 within omega-3 and dry eye supplements: published research, doctor adoption, patient adoption and reviews.
- Published research677 scored studies; evidence moderate
- Doctor adoption84#1 of 18 in omega-3 and dry eye supplements by units ordered
- Patient adoption87#1 of 29 in omega-3 and dry eye supplements by patient units
- Reviews884.40 out of 5 from 184 verified reviews
Published research67 / 100
- What was studied
- Tear film support
- Match to this product
- Same formula or device: studies count in full
-
Randomized trialJAMA Ophthalmol, 2024
Re-Esterified Triglyceride omega-3 Fatty Acids in Dry Eye Disease With Meibomian Gland Dysfunction: A Randomized Clinical Trial
Primary outcome (OSDI change) did not differ from grape-seed oil at 6 or 12 weeks; TBUT and some lid-margin signs favored omega-3 as secondary, hypothesis-generating outcomes.
-
Randomized trialBr J Ophthalmol, 2021
Effects of the re-esterified triglyceride (rTG) form of omega-3 supplements on dry eye following cataract surgery
OSDI, DEQ, corneal staining and MMP-9 improved more with omega-3; TBUT and Schirmer did not change.
-
Randomized trialCornea, 2016
Effect of Oral Re-esterified Omega-3 Nutritional Supplementation on Dry Eyes
Tear osmolarity, TBUT, MMP-9 positivity and OSDI improved versus control at 12 weeks; Schirmer, staining and MGD stage did not differ.
-
Randomized trialJ Ocul Pharmacol Ther, 2025
A Multicenter, Randomized, Clinical Trial Assessing the Effect of rTG-Omega 3 Supplementation on Meibomian Gland Dysfunction Patients after Cataract Surgery
TBUT, corneal staining, meniscometry, SPEED and OSDI improved versus control; MGD parameters did not differ overall.
Study results describe the people studied. They do not predict how any one patient will respond.
Doctor adoption84 / 100
- Rank in category
- #1 of 18 by units ordered
- Ordering practices
- 66 in 92 days
- Repeat orders
- 26 repeat orders from 66 practices in 92 days
- Window
- 11 Aug to 10 Nov 2026
Orders and reorders from practices in the Dry Eye Rescue network only, ranked within omega-3 and dry eye supplements.
Patient adoption87 / 100
- Rank in category
- #1 of 29 by patient units
- Patients
- 3,706 patients bought it in 12 months
- Repeat orders
- 3,763 repeat orders from those patients
- Window
- 12 months to 10 Nov 2026
How many Dry Eye Rescue patients buy this product and buy it again, ranked within omega-3 and dry eye supplements. Pack sizes are combined.
Reviews from patients and doctors88 / 100
4.4 out of 5184 verified patient reviews, all pack sizes, nothing filtered
Doctor notes from verified ordering practices are coming soon.
Sources and methodHow we got this
- Research: peer-reviewed studies from PubMed and other medical indexes, scored by our clinical team on how closely each matches this product.
- Doctor adoption: Dry Eye Rescue wholesale orders and reorders, ranked within omega-3 and dry eye supplements.
- Patient adoption: Dry Eye Rescue retail orders and repeat orders from patients over 12 months, ranked within omega-3 and dry eye supplements.
- Reviews: verified purchase reviews on Dry Eye Rescue.
- Schedule: re-rated every quarter. Changes of 5 points or more are checked by our team before they go live.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
CLINIC ESSENTIALS
Add the Rx You Use Every Day
Already ordering your OTC inventory? Add commonly used clinic medications to the same order.
NDC 24208-730-06
NDC 24208-585-64
![Tobramycin Dexamethasone [TOBRADEX] 0.3%/0.1% 2.5mL](http://wholesale.dryeyerescue.com/cdn/shop/files/RX-1056-Tobramycin-Dexamethasone-01.jpg?v=1784151141&width=480)
NDC 24208-295-25
More from EyePromise
Explore more products from the same brand.
Practices also stock
Complementary products other practices order alongside this one.
