In-Office Procedures · Thermoelectric Lid Therapy

MiBo Thermoflo Thermoelectric heat therapy for the eyelids.

MiBo Thermoflo (MiBoFlo) is a non-invasive thermal treatment for Meibomian Gland Dysfunction (MGD). A handheld probe delivers continuous, thermoelectrically controlled heat to the outer eyelid at a steady 108.5°F (about 42°C), paired with ultrasound gel for a gentle massage.

MiBo Thermoflo system
108.5°FSteady treatment temperature (~42°C)
~20 minTypical bilateral treatment
4Temperature modes (IIx Dual)
0Disposable tips or click fees

How it works

Continuous controlled heat

A proprietary thermoelectric (Peltier) heat pump warms a silver treatment pad that is moved over the outer eyelid with ultrasound gel. Sustained heat is designed to help liquefy hardened meibum so it can be expressed and returned to the tear film's lipid layer.

A soothing treatment

MiBoFlo gently heats the meibomian glands in a soothing, spa-like treatment, and many patients report comfort the same day.

No disposables

No disposable treatment tips, click fees or recurring per-treatment costs. The eyepad is simply cleaned between patients.

Delegable to staff

A simple, efficient workflow that can be delegated to trained staff and fits into any comprehensive dry eye program.

Published clinical research

More than a decade of published research shows measurable improvements in dry eye symptoms, meibomian gland function, tear-film stability, ocular surface health and patient-reported outcomes.

Gomez et al. 2022; Gomez et al. 2024

How MiBo Thermoflo is built

A compact tabletop unit with a touch screen, a thermoelectric heat pump and handheld probes that treat through the outer eyelid.

  • No disposable tips or click fees
  • Treats upper and lower lids
  • Delegable to trained staff
  • Thermoelectric heat pump

    Proprietary Peltier technology holds a steady therapeutic temperature, unlike warm compresses, which cool rapidly.

  • .925 silver treatment pad

    Sterilizable, interchangeable silver pads transfer controlled heat to the eyelid and are cleaned between patients.

  • Ultrasound gel massage

    Ultrasound gel couples the heated pad to the eyelid for a gentle massage that helps soften meibum.

  • Dual handpiece

    The IIx Dual's PD-adjustable dual handpiece treats both eyes at once, with detachable heaters for single-eye use.

The procedure

A provider-controlled treatment

MiBoFlo is a manual treatment. Pressure, movement, duration and precision are adjusted based on patient and clinician feedback.

About 20 minutes

Upper and lower eyelids can be treated at the same time, and most bilateral treatments are completed in about 20 minutes.

Heat, then expression

Sustained heat through the outer eyelid is designed to soften inspissated meibum, which is then expressed to help support the tear film's lipid layer.

A course of treatments

MGD is a chronic, progressive disease, so repeated treatments are recommended to help normalize meibum quality, improve gland performance and stabilize the tear film over time.

Specifications

Technical specifications
Treatment temperature 108.5°F (~42°C), Normal mode
Temperature modes, ThermoFlo IIx Dual Low (-1%), Normal (108.5°F), High (+1%), Ultra (+1.5%)
Temperature modes, ThermoFlo I Normal (108.5°F) and Low
Heat source Thermoelectric (Peltier) heat pump
Treatment pad .925 silver, sterilizable and interchangeable
Coupling medium Ultrasound gel
Touch screen 4.3 in (ThermoFlo I); 5 in (IIx Dual)
Handpiece Single handpiece (ThermoFlo I); PD-adjustable dual handpiece with 90-degree rotating cord mount (IIx Dual)
Dimensions 6 x 8.5 x 4 in (ThermoFlo I); 6.25 x 8.5 x 4 in (IIx Dual)
Weight 3 lb (ThermoFlo I); 4 lb (IIx Dual)
Manufactured in Texas, USA

Common questions about MiBo Thermoflo

Does MiBoFlo liquefy meibomian gland secretions?

Yes. MiBoFlo uses thermoelectric heat designed to soften inspissated meibum, which can help gland expression and support the tear film in patients with MGD.

How is MiBoFlo different from a warm compress?

Warm compresses cannot consistently reach or hold therapeutic temperatures and cool rapidly. MiBoFlo uses thermoelectric (Peltier) technology to deliver a controlled temperature of about 108°F (42°C) through a .925 silver treatment pad and ultrasound gel.

Does treatment need to be applied to the inner eyelid?

No. The meibomian glands lie within the tarsal plate, and MiBoFlo generates enough thermal energy to warm them through the eyelid tissues. Real-time temperature measurements confirm therapeutic tissue temperatures during treatment.

Can upper and lower eyelids be treated at the same time?

Yes. MiBoFlo has sterilizable, interchangeable treatment pads, and most bilateral treatments take about 20 minutes.

Why are multiple treatments recommended?

MGD is a chronic, progressive disease rather than a one-time obstruction. Repeated thermal therapy can help normalize meibum quality, improve gland performance and stabilize the tear film over time.

Peer-reviewed clinical studies

  • Gomez ML, Afshari NA, Gonzalez DD, Cheng L. Effect of Thermoelectric Warming Therapy for the Treatment of Meibomian Gland Dysfunction. Am J Ophthalmol. 2022;242:181-188. PubMed
  • Gomez ML, Jung J, Gonzales DD, Shacterman S, Afshari N, Cheng L. Comparison of Manual versus Automated Thermal Lid Therapy with Expression for Meibomian Gland Dysfunction in Patients with Dry Eye Disease. Sci Rep. 2024. doi:10.1038/s41598-024-72320-3. PubMed
  • Li S, Yang K, Wang J, et al. Effect of a Novel Thermostatic Device on Meibomian Gland Dysfunction: A Randomized Controlled Trial in Chinese Patients. Ophthalmol Ther. 2022;11:261-270. PubMed
  • Mehta NN, Nagel ID, Agnihotri A, et al. Dry Eye Disease Treatment Improves Subjective Quality-of-Life Responses in Patients with AMD, Independent of Disease Stage. PLoS One. 2025;20:e0318733. PubMed
  • Sarhan AAE, Marey HM, Zaky MA, Soliman LS. Effect of MiBoFlo Treatment in Dry Eye Patients with Meibomian Gland Dysfunction. Egypt J Hosp Med. 2026;103:2118-2128.

Add MiBo Thermoflo to your dry eye program

A thermoelectric lid therapy for MGD with no disposable tips or per-treatment fees, delivered by doctors or trained staff in about 20 minutes.

MiBo Thermoflo is a trademark of MiBo Medical Group. Review the full manufacturer instructions for use, including all warnings, precautions and contraindications, before use. Individual results vary.