In-Office Procedures · Diagnostic

ScoutPro Tear Osmolarity System

A single objective number to grade dry eye severity and track treatment response, measured at the chair in seconds from a nanoliter tear sample.

Key points

  • Available on the Dry Eye Rescue wholesale platform.
  • One objective osmolarity number grades dry eye severity at the chair.
  • Measured in seconds from a tiny tear sample.
  • Rising or unstable readings track disease and treatment response.

What it does

The ScoutPro (Trukera Medical) measures tear film osmolarity from a 50-nanoliter sample collected at the outer canthus. The result, expressed in milliosmoles per liter (mOsm/L), is the single most objective marker of dry eye disease severity and reflects the breakdown of tear film homeostasis. Both eyes are sampled and reported independently; inter-eye asymmetry (≥8 mOsm/L) is itself a diagnostic marker of disease, even when absolute values fall below threshold.

Why osmolarity matters clinically

The TFOS DEWS II and DEWS III reports identify tear hyperosmolarity as a core mechanism in the vicious cycle of dry eye disease, triggering ocular surface inflammation, goblet cell loss, and further tear film instability. Osmolarity testing gives clinicians a quantitative baseline before treatment begins and an objective measure of whether any intervention, drops, thermal pulsation, punctal plugs, or anti-inflammatories, is actually working.

  • Normal: <308 mOsm/L
  • Mild to moderate dry eye: 308 to 320 mOsm/L
  • Moderate to severe: >320 mOsm/L
  • Clinically significant inter-eye asymmetry: ≥8 mOsm/L

Clinical evidence

  • Sullivan et al. (2010), Ophthalmology, Foundational validation study establishing osmolarity as the single best-performing diagnostic marker for dry eye disease, with higher sensitivity and specificity than TBUT, Schirmer, or staining alone. PubMed
  • Potvin et al. (2015), Clinical Ophthalmology, Demonstrated that elevated osmolarity can scatter light equivalent to a moderate cataract, and predicts visually significant dry eye after surgery. PMC
  • TFOS DEWS III Management and Therapy Report (2025), Reaffirms osmolarity testing in the core diagnostic workup as a baseline measure to follow treatment response. American Journal of Ophthalmology

How it fits in practice

Osmolarity is typically the first objective test in the dry eye workup, performed before any drops, before tonometry, and before contact lens manipulation. Results take under a minute and directly inform whether anti-inflammatory therapy, punctal occlusion, or aggressive lid treatment is warranted. Repeat testing at follow-up visits documents objective improvement and reinforces patient compliance.

Manufacturer

Trukera Medical, trukera.com

Availability on Dry Eye Rescue

We carry the ScoutPro console and the single-use test cards. Contact Provider Relations for system pricing and auto-ship card programs.

Sources are linked inline above. Device descriptions reference FDA clearance status, published peer-reviewed studies, and manufacturer data. Clinical outcomes are not a guarantee of individual results. Review full prescribing information, the IFU, and FDA clearance documentation for each device before use.

Add osmolarity to your workup