Description
NDC: 61314-665-05
Apraclonidine HCl 0.5% Ophthalmic Solution, 5 mL — Sandoz
| Active ingredient | Apraclonidine hydrochloride equivalent to 5 mg apraclonidine base per mL (0.5%) |
| Dosage form | Ophthalmic solution |
| Route | Topical ophthalmic |
| Size | 5 mL |
| Manufacturer | Sandoz |
| NDC | 61314-665-05 |
Indications and Usage
Short-term adjunctive therapy in patients on maximally tolerated medical therapy who require additional reduction of intraocular pressure.
Dosage and Administration
Instill one to two drops in the affected eye(s) three times daily. Patients using the drug to control intraocular pressure should be monitored for a possible loss of effect over time.
Warnings and Precautions
- For topical ophthalmic use only; not for injection or oral use
- Use caution in patients with severe cardiovascular disease including hypertension
- Use caution in patients with renal or hepatic impairment
- Loss of intraocular-pressure-lowering effect (tachyphylaxis) may occur over time
Contraindications
Contraindicated in patients hypersensitive to apraclonidine or clonidine and in patients receiving monoamine oxidase inhibitors.
Adverse Reactions
The most common adverse reactions are ocular hyperemia, pruritus, discomfort, tearing, and lid edema, along with dry mouth; allergic-like ocular reactions are the most frequent cause of discontinuation.
Storage and Handling
Store at 2°C to 25°C (36°F to 77°F); protect from freezing and from light.
How Supplied
Sterile 0.5% solution in plastic dropper dispenser bottles, supplied in 5 mL and 10 mL sizes.
Professional use only. Clinical information summarized from FDA-approved prescribing information (Structured Product Labeling); refer to the full prescribing information via DailyMed for complete details.
