Description
NDC: 0409-4283-01
Lidocaine HCl 4% (Preservative-Free) Injection, 5 x 5 mL Ampules — Hospira
| Active ingredients | Lidocaine hydrochloride 40 mg/mL (4%), 200 mg per 5 mL, preservative-free |
| Dosage form | Sterile injectable solution, preservative-free (MPF) |
| Route | Local infiltration and regional nerve block (including retrobulbar); topical anesthesia of respiratory mucous membranes |
| Size | 5 mL single-dose ampule, 5 ampules per pack |
| Manufacturer | Hospira |
| NDC | 0409-4283-01 |
Indications and Usage
Production of local or regional anesthesia by infiltration and peripheral nerve block techniques, including retrobulbar block, and topical anesthesia of the mucous membranes of the respiratory tract.
Dosage and Administration
For a 70 kg adult, retrobulbar injection typically uses 3-5 mL (120-200 mg) and transtracheal use 2-3 mL. Total dose should not exceed approximately 4.5 mg/kg (up to 300 mg); reduce for pediatric patients.
Warnings and Precautions
- Should be used only by clinicians trained in managing local anesthetic toxicity
- Risk of methemoglobinemia
- Aspirate before injection to avoid intravascular administration
- Chondrolysis reported with intra-articular infusion (an unapproved use)
Contraindications
Known hypersensitivity to amide-type local anesthetics.
Adverse Reactions
CNS effects including tremor, dizziness, and seizures with respiratory depression, and cardiovascular depression such as bradycardia, hypotension, and cardiovascular collapse; allergic reactions are rare with amide anesthetics.
Storage and Handling
Store at 20°C to 25°C (68°F to 77°F), USP controlled room temperature; discard unused portion (single-dose, preservative-free).
How Supplied
Single-dose, preservative-free 5 mL ampules packaged 5 per carton.
Professional use only. Clinical information summarized from FDA-approved prescribing information (Structured Product Labeling); refer to the full prescribing information via DailyMed for complete details.
