Cortisol Calm by Pure Encapsulations
Support healthy cortisol. Reduce stress. Relieve dry eyes.
What Is Cortisol Calm?
Cortisol Calm is a clinical-strength supplement formulated to lower high cortisol levels, reduce stress, and support healthy adrenal function. For people experiencing chronic dry eyes linked to stress, anxiety, or hormonal imbalance, this product targets one of the core systemic drivers of inflammation.
Dry Eyes and Cortisol: What’s the Link?
New findings from the 2025 TFOS DEWS III Report show a clear connection between elevated cortisol, chronic stress, and dry eye disease (DED):
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High stress activates the hypothalamic-pituitary-adrenal (HPA) axis, which raises cortisol and disrupts immune homeostasis.
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Cortisol dysregulation leads to chronic inflammation, tear film instability, and ocular surface damage.
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Patients with anxiety, PTSD, burnout, or hormonal shifts (like menopause) are especially vulnerable to stress-exacerbated DED.
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Emotional stress and psychiatric disease are now confirmed modifiable risk factors for dry eye, meaning they can and should be treated to improve symptoms.
How Cortisol Calm Helps
Cortisol Calm works by downregulating the body’s stress response, balancing cortisol, and reducing systemic inflammation—indirectly improving tear function and ocular comfort.
Core benefits:
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Reduces elevated cortisol with clinically proven adaptogens
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Promotes calm and clarity without sedation
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Improves stress resilience and recovery
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Supports mood, focus, and sleep—all factors linked to ocular surface health
Key Ingredients & Function
| Ingredient |
Function |
| Ashwagandha (KSM-66®) |
Reduces cortisol, balances HPA axis |
| Rhodiola rosea |
Increases stress tolerance, boosts energy |
| L-Theanine |
Induces alpha brain waves, promotes calm alertness |
| Phosphatidylserine |
Lowers cortisol, supports memory and mood |
Who Should Take This
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Anyone with dry eyes linked to chronic stress
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Patients with refractory DED not responding to topical therapy
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People with anxiety, PTSD, or insomnia and concurrent eye symptoms
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Postmenopausal women or individuals with known hormonal imbalance
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Anyone who says “my eyes get worse when I’m stressed”
Directions for Use
Take 2 capsules daily with food. Use consistently for at least 4 weeks to regulate cortisol levels and reduce inflammatory load.
FAQ: Cortisol, Stress, and Dry Eyes
Q: Can high cortisol cause dry eyes?
Yes. Elevated cortisol from chronic stress disrupts immune regulation and worsens inflammation on the ocular surface. This leads to symptoms like dryness, irritation, and burning.
Q: How do I know if stress is causing my dry eyes?
If your symptoms flare during high-stress periods, lack of sleep, emotional burnout, or anxiety, cortisol imbalance could be a driving factor. Hormonal changes (e.g., menopause) also amplify this.
Q: Will Cortisol Calm work if I’m already using dry eye drops?
Yes. Cortisol Calm addresses the root cause—stress and inflammation—while drops only treat symptoms. Together, they offer a more complete dry eye protocol.
Q: How long before I see results?
Most users feel calmer within 1–2 weeks. Ocular symptoms may begin improving within 3–4 weeks as systemic inflammation decreases.
Q: Is Cortisol Calm safe for long-term use?
Yes. It’s non-sedating, non-habit forming, and uses well-researched, adaptogenic herbs suitable for long-term HPA axis support.
Q: Can it help with other symptoms like fatigue or brain fog?
Absolutely. Many users report better energy
